Preoperative care is the foundation of successful surgical outcomes. A thorough preoperative assessment identifies potential risks, optimizes patient condition, and ensures informed consent. This comprehensive guide covers essential principles every medical student and junior doctor must master for safe perioperative care and excellent clinical practice.
The Preoperative Assessment Framework
1. Comprehensive History Taking
Current Condition: Understand the indication for surgery, symptom duration, severity, and impact on daily activities. Document any emergency red flags that might affect timing or approach.
Past Medical History: Screen for conditions that increase surgical risk:
- Cardiovascular disease (MI, heart failure, arrhythmias)
- Respiratory disease (COPD, asthma, OSA)
- Diabetes mellitus and glycemic control status
- Renal or hepatic impairment
- Neurological disorders (stroke, seizures)
- Bleeding disorders or thrombophilia
Previous Surgeries: Document all prior operations, anesthetic complications, difficult intubation, PONV (postoperative nausea/vomiting), or prolonged recovery. Family history of anesthetic problems like malignant hyperthermia is crucial.
Medications: Review all current medications including over-the-counter and herbal supplements. Key considerations:
- Anticoagulants/antiplatelets (timing of cessation/bridging)
- Antihypertensives (continue most, hold ACE-I/ARBs on surgery day)
- Diabetic medications (adjust insulin/oral agents)
- Steroids (stress dose coverage if chronic use)
- Immunosuppressants (infection risk assessment)
For drug interactions, see our Pharmacology Guide.
2. Functional Capacity Assessment
Functional capacity predicts perioperative risk. Use the Metabolic Equivalent (MET) system:
- Excellent (>10 METs): Running, heavy labor - low risk
- Moderate (4-10 METs): Climbing stairs, housework - moderate risk
- Poor (<4 METs): Minimal activity tolerance - high risk
Patients unable to walk 2 blocks or climb 2 flights of stairs without symptoms need further cardiac evaluation.
Risk Stratification Tools
ASA Physical Status Classification
- ASA I: Healthy patient, no systemic disease
- ASA II: Mild systemic disease (controlled HTN, smoking)
- ASA III: Severe systemic disease (poorly controlled DM, COPD)
- ASA IV: Severe disease threatening life (recent MI, sepsis)
- ASA V: Moribund patient not expected to survive without surgery
- ASA VI: Brain-dead patient for organ donation
- E suffix: Emergency surgery (increases risk)
Higher ASA scores correlate with increased perioperative morbidity and mortality. Learn more at ASA Guidelines.
Cardiac Risk Assessment
Revised Cardiac Risk Index (RCRI): Identifies patients at risk for cardiac complications:
- High-risk surgery (intraperitoneal, intrathoracic, vascular)
- Ischemic heart disease
- History of congestive heart failure
- History of cerebrovascular disease
- Diabetes requiring insulin
- Preoperative creatinine >2 mg/dL
Each factor = 1 point. 0 points = 0.4% risk, 1 point = 1%, 2 points = 2.4%, ≥3 points = 5.4% risk of major cardiac events. For more on cardiovascular assessment, visit ACC Clinical Guidelines.
Essential Preoperative Investigations
Laboratory Tests
Routine for all patients:
- Complete Blood Count (anemia, infection, thrombocytopenia)
- Blood group and typing (cross-match if blood loss expected)
- Coagulation profile (PT/INR, aPTT) if bleeding risk
Condition-specific:
- Renal function (urea, creatinine, electrolytes) - age >65, renal disease, cardiac disease
- Liver function tests - hepatic disease, alcohol abuse
- HbA1c - diabetic patients (target <8% for elective surgery)
- Pregnancy test - women of childbearing age
Imaging Studies
- Chest X-ray: Age >60, cardiopulmonary disease, malignancy
- ECG: Age >40-50, cardiovascular risk factors, symptoms
- Echocardiography: Symptomatic valve disease, heart failure
- Pulmonary function tests: Thoracic surgery, severe COPD
Patient Optimization Strategies
Cardiovascular Optimization
- Hypertension: Target BP <140/90, continue beta-blockers
- Recent MI/stent: Delay elective surgery (bare-metal stent 6 weeks, drug-eluting 12 months)
- Heart failure: Optimize volume status, consider diuretics
- Arrhythmias: Control rate, correct electrolytes
Respiratory Optimization
- Smoking cessation (ideally 8 weeks before, minimum 24-48 hours)
- Optimize bronchodilators and steroids for COPD/asthma
- Treat active respiratory infections (delay if possible)
- Consider incentive spirometry training preoperatively
Metabolic Control
- Diabetes: HbA1c <8%, avoid hypoglycemia, adjust insulin regimen
- Thyroid: Achieve euthyroid state before elective surgery
- Nutritional: Correct severe malnutrition, consider preoperative nutrition support
Preoperative Fasting Guidelines
Follow the "2-4-6 Rule" to reduce aspiration risk while avoiding dehydration:
- Clear fluids: Up to 2 hours before surgery
- Breast milk: Up to 4 hours before surgery
- Light meal: Up to 6 hours before surgery
- Heavy/fatty meal: Up to 8 hours before surgery
These guidelines reduce gastric volume and acidity while maintaining hydration. For more details, see ASA Practice Guidelines.
Antibiotic Prophylaxis
Surgical site infections increase morbidity and costs. Prophylactic antibiotics should be:
- Given within 60 minutes before incision (120 min for vancomycin/fluoroquinolones)
- Appropriate spectrum for expected pathogens
- Redosed if surgery >2 half-lives or significant blood loss
- Discontinued within 24 hours post-op (cardiac surgery 48 hours max)
Common regimens:
- Clean procedures: Usually not needed unless prosthetic material
- Clean-contaminated: Cefazolin 2g IV
- GI/colorectal: Cefazolin + metronidazole or cefoxitin
- MRSA risk: Add vancomycin to regimen
Venous Thromboembolism Prophylaxis
Assess VTE risk using validated tools (Caprini, Rogers scores). Stratify and implement:
Low risk: Early mobilization, adequate hydration
Moderate risk: Mechanical prophylaxis (compression stockings, intermittent pneumatic compression)
High risk: Pharmacological prophylaxis (LMWH, unfractionated heparin) + mechanical
Continue prophylaxis until fully mobile or hospital discharge. Some high-risk patients need extended prophylaxis (up to 4 weeks for cancer/orthopedic surgery).
Informed Consent
Valid consent requires:
- Capacity: Patient can understand and retain information
- Information: Nature of procedure, benefits, risks, alternatives
- Voluntariness: No coercion or undue pressure
Discuss common and serious risks specific to the procedure. Document the conversation thoroughly. For complex cases, involve family members (with patient permission).
Day-of-Surgery Checklist
- Confirm patient identity, procedure, and site (use WHO checklist)
- Mark surgical site if laterality involved
- Verify NPO status and last oral intake
- Remove jewelry, dentures, contact lenses
- Ensure IV access established
- Review medication administration (which held, which given)
- Confirm blood products available if needed
- Complete surgical safety checklist (sign-in, time-out, sign-out)
Special Populations
Elderly Patients
- Assess cognitive function and delirium risk
- Review polypharmacy and drug interactions
- Evaluate frailty and functional dependence
- Plan for postoperative delirium prevention
Pediatric Patients
- Parental involvement in consent and preparation
- Age-appropriate fasting (shorter times for infants)
- Behavioral preparation and anxiety reduction
- Temperature regulation (higher surface area:volume)
Pregnant Patients
- Defer elective surgery until postpartum
- Second trimester safest for essential surgery
- Monitor fetal heart rate, involve OB team
- Left lateral tilt positioning (after 20 weeks)
For obstetric considerations, see our Obstetrics Guide.
External Resources
- American Society of Anesthesiologists
- ACS NSQIP - Surgical Quality
- WHO Surgical Safety Checklist
- UpToDate - Preoperative Evaluation
Conclusion
Thorough preoperative assessment and optimization are critical for patient safety and surgical success. A systematic approach identifying and mitigating risks improves outcomes and reduces complications. Regular practice and adherence to evidence-based guidelines ensure high-quality perioperative care. Test your knowledge with our Question Bank and explore more surgical topics in our blog section.